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Nevertheless, it is of special importance to highlight that, according to the research study findings on the subject of the above-mentioned pathophysiological mechanisms, cryoablation has been found to demonstrate variable and less controllable effectiveness as each tissue cell is affected by and reacts to different thermal histories, such as cooling temperature and rate, time of exposure, hold time, and end temperature, resulting in variable degrees of cell injury
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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood
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