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normalized weight and body and femur length to conventionally raised mice), suggesting that gut microbiota impact IGF-1 levels and thus growth [48]

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“The implication of this current study is for people with severe asthma who are currently eligible for treatment with tezepelumab, and the new evidence it brings is a tested protocol which doctors can use to guide the safe reduction of oral steroids in these patients as they move onto tezepelumab.” She added: “The findings provide more evidence about how, for people with severe asthma, biologics can help to shift the dependence away from oral steroids — which we know have concerning side effects for people with asthma who have been using them long term