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It also modulated T cell subset balance by suppressing effector T cells (e.g., T follicular helper and Th17 cells) and promoting regulatory T cells, thereby slowing the progression of pSS ( 2.2.3 Regulation of complement activity The complement system, composed of over 30 plasma proteins, is a sophisticated cascade reaction mechanism that plays a critical role in bridging innate and adaptive immunity ( Table 1 )
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