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Keep in mind that reduced glutamate uptake by EAAT2 causes more glutamate to remain in the synapse
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AngII also increases the expression of MMP-2 in the vasculature by activating p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinases (ERK) 1 and 2, c-Jun N-terminal Kinase (JNK) and the transcription factor activator protein (AP)-1 (Kopaliani et al., 2014)
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