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Low arginine appears to play a role in the pathogenesis of a number of varied diseases , including cardiovascular disease, acute asthma, pulmonary hypertension, cystic fibrosis, sickle cell disease, trauma, and certain cancers, among others

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Recent studies have corroborated these results (Reference Al-Harbi, Imam and Nadeem22–Reference Bashandy, Ebaid and Moussa26,Reference Naseem, Hassan and Alhazza28,Reference Salman and Naseem29,Reference Alam, Iqbal and Naseem31,Reference Jiang, Chen and Liu33–Reference Tang, Wen and Guo36)