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Notably, 1-MNA demonstrates thrombolytic properties in vivo by inhibiting platelet-mediated thrombosis through activation of the cyclooxygenase-2 (COX-2)–prostacyclin (PGI 2 ) pathway
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Esses estudos quantificam parâmetros pré-clínicos relevantes para a resposta do tecido articular e a patologia estrutural dentro das limitações do sistema modelo, apoiando a investigação laboratorial de ambientes de sinalização associados à cartilagem e da biologia da remodelação da matriz .6]
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